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Oxidative denaturation of the protein reduces the erythroblasts membranes deformability and makes it more susceptible to clearance by immune organs such as the spleen, ultimately leading to anemia (Pantaleo et al., 2008)

Moyrand F, Klaproth B, Himmelreich U, Dromer F, Janbon G

Symptoms of this type of carnitine deficiency, which include cardiomyopathy, skeletal-muscle weakness, and hypoglycemia, typically present by 5 years of age

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Long noncoding RNAs (lncRNAs) are novel class of regulatory RNAs, which are involved in numerous biological processes via interaction with mRNAs and miRNAs, such as miRNA and lncRNA competition for the same mRNA target, and lncRNAs acting as decoys (or sponges) for miRNAs [154]