epithalon vs gdf11 GDF-11 Systemic GDF11 attenuates depression-like phenotype

Systemic GDF11 attenuates depression like phenotype in aged mice via stimulation of neuronal autophagy Nature Aging The versatility and paradox of GDF 11 ScienceDirect Rather than a rejuvenating agent, GDF11 may have a detrimental effect on liver senescence. Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy [2021, open access] : r longevity GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis Molecular Brain Springer Nature Link GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration: Cell Metabolism

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