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The letters CJC dont mean anything special, they are thought to be the initials of the company that developed it, ConjuChem Biotechnologies

That distinction separates them from injectable human growth hormone (HGH) and is the key to understanding both their appeal and their limits

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For patients with clinical deficiency, effective replacement therapy should lead to a normal blood count after two months of treatment, while improvement in neurologic symptoms begins within one week after initiation of therapy and is usually complete within 6 weeks to 3 months.13 For patients with an asymptomatic biochemical deficiency (ie, subclinical disease), measurement of serum B12 or MMA levels should be done 2 to 3 months after initiation of replacement therapy.12 Once metformin is started, this medication is seldom discontinued unless advanced renal impairment develops

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