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For lipid peroxide production measurements using C11- BODIPY (581/591) (2 mM) (Thermofischer, Waltham, MA), 2x10 5 cells were labeled with C11-BODIPY in 1 mL of warm complete medium for 10 min in a tissue culture incubator (37C, 5% CO 2 ) in the dark

This study highlights OIs promising role in treating IBD

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It has been demonstrated that GPX4 is significant in protecting Treg cells from undergoing lipid peroxidation and ferroptosis, thereby contributing to maintaining immune homeostasis (Xu et al., 2021)

Curcumin can also compete with LPS for TLR4 receptor activation, thereby inhibiting the TLR4/myeloid differentiation 88 (MyD88)/NF-B signaling pathways (150, 151)