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doi: 10.1007/s40279-021-01502-0

Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-kappaB signaling pathway

designed a US-triggered MnWO X nanosystem modified with PEG (termed MnWO X -PEG) to endow the capability of GSH-enhanced ROS ( 1 O 2 and OH) production for killing malignant tumors (Figure 6D) ( X -PEG exhibited significantly time-dependent GSH consumption capacity through reducing W 6+ to W 5+ (Figure 6E), cooperating with increased ROS to achieve a powerful inhibition effect on tumors (Figure 6F)

Editor information Editors and Affiliations Rights and permissions Copyright information 2019 Springer Nature Switzerland AG About this chapter Cite this chapter Takagi, H

Bagheri E, Abnous K, Farzad SA, Taghdisi SM, Ramezani M, Alibolandi M