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Thus, hemeHPX endocytosis and heme delivery lead to the induction of several protective proteins (Larsen et al., 2010) and likely maintain intracellular levels of reduced glutathione

The most common treatment-related adverse events (TEAEs) were elevated hepatic transaminases (including aspartate transaminase and alanine transaminase), fatigue, and hypertension

Post-mortem studies also find differences between treated and untreated patients with schizophrenia, showing a positive correlation between the density of GAD and antipsychotic dose and higher expression levels of GAD67 and GABA-A protein subunits in antipsychotic-treated patients relative to unmedicated patients [49]

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