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Dysbiosis leads to altered levels of key metabolites: reduced SCFAs (e.g., butyrate, acetate) impair support for Treg cell differentiation and inhibition of Th17 responses, while compromising intestinal barrier integrity

NAD+ (Nicotinamide Adenine Dinucleotide) is a cofactor compound found in all living cells

Furthermore, insulin levels were positively correlated with metabolic markers and high-sensitivity C-reactive protein (hs-CRP), and negatively correlated with sperm count, motility, and morphology [32]