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Furthermore, of the 201 variants with nucleotide substitutions, 200 were missense variants instead of nonsense variants, meaning that the mutations cause a change in amino acid rather than a premature termination of translation

Tominaga K, Hongo N, Fujishita M, Takahashi Y, Adachi Y (2017) Protective effects of astaxanthin on skin deterioration

Nat Rev Neurol 19:715736

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Biochemistry of Acetyl-L-Carnitine This compound is the acetylated form of L-carnitine, meaning it has an acetyl group attached to its molecular structure