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Metabolic studies showed that AOD9604-treated animals had increased lipolytic rates measured in isolated adipocytes, elevated circulating free fatty acid levels, and enhanced fatty acid oxidation rates

While early animal studies show potential fat-loss effects, no evidence confirms safety or efficacy in people

Heavy-chain antibody targeting of CD38 NAD+ hydrolase ectoenzyme to prevent fibrosis in multiple organs

Grip strength increased by approximately 60% when the compound was combined with rigorous exercise training, compared to about 25% improvement from either exercise or treatment alone

A 12-week Phase IIa trial involving 300 participants showed modest reductions in weight (2.6 kg versus 0.8 kg for placebo)