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It participates in one-carbon metabolism and is converted to oxaloacetate or formic acid through the glycine cleavage system (GCS), while simultaneously releasing ammonia and carbon dioxide

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GenBank AA305285 EST176272 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end similar to similar to actin, gamma 1, mRNA sequence

The FR-targeting feature of DS-FPM demonstrates promising potential as a delivery platform for combination therapeutics (siRNA and DXP) in RA treatment

[PubMed] [Google Scholar] 28.OSullivan AJ, Martin A, Brown MA