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[90] The extent to which alterations in the brain caused by nicotine use are reversible is not fully understood

Ernest Thompson Seton, The Boy Scouts in America, Outlook (July 1910): 633, as quoted in Phillip J

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Langenbecks Arch Surg 393(4):535545 Muscat JE, Djordjevic MV, Colosimo S, Stellman SD, Richie JP (2005) Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)