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doi: 10.1016/j.tcm.2016.03.001 342 ShaoXMLpez-ValdsHELiangJFeldmanJL

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However, when present in normal concentrations, A does not induce oxidative stress, but when the amount of A increases significantly, as it does in AD, it evolves into a pro-oxidant that enhances oxidative stress, leading to disease progression (Rani et al., 2017)