MaP555 Acid (cell-permeable fluorogenic dye) tmr selective and orally bioavailable small-molecule

selective and orally bioavailable small-molecule SHP2 inhibitor

Product Name BG-DOTA Synonyms SNAP-DOTA CAS Number n/a Related CAS Molecular Formula C29H40N10O8 Molecular Weight 656

In addition

458 SMILES [N-]=[N+]=NCCOCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It is also a good transglutaminase substrate for site-specific protein labeling like FITC cadaverine

MaP555 Acid (cell-permeable fluorogenic dye) tmr selective and orally bioavailable small-moleculeMaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The good spectroscopic properties, high cell