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The most abundant types of enzyme-mediated crosslinks within adult tendon are mature trivalent HP (HP or HylPyr, or pyridinoline, 428 Da) crosslinks composed of two telopeptide Hyl and one helix Hyl and, to a lesser extent, trivalent LP (LP or LysPyr, or deoxypyridinoline, 412 Da) crosslinks composed of two telopeptide Hyl and one helix lysine (Fig

doi: 10.1007/978-1-4020-6486-9_8 89 BurrageLCThistlethwaiteLStroupBMet al

YAP can drive glucose uptake and glycolysis partially via the glucose transporter (GLUT)

Finally, non-protein nitrogen (NP ) group may comprise a large number of molecules in whey, among which urea may account for 50-60%)

Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon