OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA Size:1mg Product Name tert-butyl 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}acetate Synonyms

Product Name tert-butyl 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}acetate Synonyms CAS Number n/a Related CAS Molecular Formula C16H32N4O2 Molecular Weight 312

457 SMILES [N-]=[N+]=NCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

6 SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCC(O)=O)[C@@]1([H])NC(=O)N2 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

295 SMILES OC(=O)CCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

where the Val-Cit-PAB motif enables enzyme-cleavable release of MMAE inside target cells

OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA Size:1mg Product Name tert-butyl 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}acetate SynonymsOSu PEG4 vc PAB DMEA Duocarmycin SA is a cleavable ADC druglinker conjugate that couples the potent antitumor antibiotic Duocarmycin SA to an OSu PEG4 vc PAB DMEA linker. The DNA? modifying agents such as duocarmycin are increasingly used in the development of antibody? drug conjugates (ADCs), where they serve as highly potent cytotoxic payloads. Designed for ADC research, this construct supports efficient antibody conjugation, PEG4? enhanced