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Several potent and selective 5-HT2Creceptor agonists proved to be effective in suppressing food intake and inducing weight loss in rodents, including WAY-163909 (41), CP-809101 (42), and vabicaserin (43)

We have previously demonstrated an increased nicotinamide:nicotinic acid ratio in the adipose tissues of 5A-1MQ-treated DIO mice 13

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