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10.1016/j.molcel.2020.11.024 177 YangF.YanG.LiY.HanZ.ZhangL.ChenS.et al (2016)

Molecular mechanisms and prevention

Sustained GH and IGF-1 elevation In Phase 1 data, a single CJC-1295 with DAC injection raised growth hormone roughly 2-10 fold for at least 6 days and IGF-1 about 1.5-3 fold for 9-11 days

Williams MA, Rangasamy T, Bauer SM, Killedar S, Karp M, Kensler TW, et al

In much larger teixobactinlipid II oligomers that we observe experimentally, the perturbations must certainly be more pronounced than in the simulated building block