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According to density functional theory (DFT), the authors proposed that the specific topological structures of CD molecules and their unique electron transfer effects with the appended Au surface lead to unpredictable catalytic properties

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Although most studies to date support a pathogenic role for TRPM2 in microglia-mediated neuroinflammation, some limitations were highlighted, as the non-selective pharmacological inhibitors available, the inclusion of only males in the majority of studies, and the use of a global TRPM2 knockout

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