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Alcohol depletes glutathione: Chronic alcohol consumption severely reduces hepatic glutathione through increased oxidative stress during ethanol metabolism [6][35]

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The end product of the oxidative phase of the PPP is ribulose 5-phosphate, which enters the nonoxidative phase of the PPP to generate ribose 5-phosphate, the backbone of nucleic acids

In the selenite-induced cataract model, the extract likely mitigated oxidative stress by scavenging reactive oxygen species, thereby preventing protein damage and maintaining the levels of essential lens proteins such as -A crystallin and aquaporin 0