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The effectiveness and purity of PCT drugs are concerns for many users ( Polypharmacy associated with AAS and PCT drugs may have serious harmful effects on those engaged in such practices, which constitutes a serious public health concern ( Although these medications are legally available only with the prescription of a doctor, they can be bought without a prescription on the Internet

NICE guidelines recommend evidence-based weight management through dietary modification (600 kcal/day deficit), 150300 minutes weekly moderate-intensity physical activity, and behavioural change strategies

Further, it activates muscle stem cells, promoting tissue regeneration, and reverses insulin resistance in relevant animal models, all with good systemic tolerability 1,2