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The anti-apoptotic activity of TB-500 may involve the reduction of early cell death initiation signals and activation of the survival kinase Akt through complex formation with PINCH and integrin-linked kinase

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39,71 This suggests the existence of an enzyme that decarboxylates DHNA to 1,4-naphthoquinone

MicroRNA antagonist therapy during normothermic machine perfusion of donor kidneys

However, the native one from pea is a homotetramer with a molecular weight of 156 kDa (the subunit molecular weight is 40 kDa), whereas the recombinant one from thale cress has monomeric and homodimeric conformations with molecular weights of 42.4 and 87.5 kDa, respectively (Gatzek et al., 2002)