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Therefore, the focus of the present study is to determine whether 4-OXO-DHA can be identified as a metabolite of DHA in vivo, to examine its effects on critical molecular targets of mammary carcinogenesis in breast cancer cell lines in vitro and to elucidate the structural basis that can account for its inhibition of NF-B

the urine from each rat was collected daily from the metabolic cages, and kept in dry ice

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