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Results and discussion Discrete late endocytic organelles and gut granules in the developing intestine Two late-stage endo-lysosomal organelles (yolk granules and lysosomes) and one LRO (gut granules) have been identified in developing intestinal cells of embryos [11, 22]

A novel regulatory defect in the branched-chain alpha-keto acid dehydrogenase complex due to a mutation in the PPM1K gene causes a mild variant phenotype of maple syrup urine disease

However, whether these factors are causally related to CAD has been questioned in MR studies [45, 46], and we found no difference by sex in the risk factors

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