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Cell scattering, which is the hallmark of an HGF/c-Met interaction, leads to a loss of cell adhesion properties that allow cells to migrate

However, it is important to describe this as modulation of signaling pathways, not as proven therapeutic effects

HLC cultures were incubated with conventional probe substrates for CYP3A4 (6 M midazolam), CYP2C9 (10 M diclofenac), and CYP2D6 (10 M dextromethorphan) for 2 hours

Thomas Rosemann is Chair of Primary Care at the University of Zurich and Director of the Institute for Primary Care at the University Hospital, Zurich (USZ)

Two people, no controls, no oral or subcutaneous data