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Tissue-specific ICAM-1 expression and neutrophil transmigration in the copper-deficient rat

Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy

Further, early secreted antigen ESAT-6-mediated nuclear translocation of transcription factor NRF-2 is required for Mtb-induced HO-1 expression (193)

For instance, post-hoc analyses of pre- and post-treatment biopsy samples from Ewing sarcoma patients treated with either IGF-1R mAb or a combination of cixutumumab and the mTOR inhibitor temsirolimus revealed that median PFS and OS was better in phospho-IGF-1R-negative patients