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Data Brief 6:194199

Therefore, we asked whether the effect of B 12 on reprogramming could be recapitulated in vitro

This includes the key transcription factor nuclear factor kappa B (NF-B), which triggers the infiltration of inflammatory cells in the pancreas and systemic inflammatory response, leading to acinar cell death through apoptosis and necrosis (9)

As the sole intracellular LPO-reducing enzyme, the lack of GPX4 results in excessive accumulation of LPO, destabilizing biological membranes, exacerbating oxidative stress, and ultimately promoting ferroptosis (Ursini and Maiorino, 2020)

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