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-y et al

The underlying mechanism is that angiotensin II binds to angiotensin II type 1 (AT1) receptor and then activates JAK/STAT signaling to induce IL-6 production

Abbreviations: AR: allergic rhinoconjunctivitis

Y.ZhangP

Although DEX increases NPT1 and NPT4, it significantly reduces OAT3 expression in mouse kidney, which also shows the complex roles of DEX on urate absorption (Li et al., 2019)