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We will continue to take appropriate measures, working hand in hand with our federal enforcement partners, to address unauthorized tobacco products, especially those most appealing to youth. This latest round of warning letters marks another step in FDAs continued efforts to remove unauthorized e-cigarette products from the market, particularly those that appeal to youth

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In addition to the sensitivity analyses, the doseresponse risk estimates were also validated by plotting the mean risk function along with its 95% UI against both the extracted dose-specific RR data from the studies included and our previous doseresponse risk estimates from the GBD 2019 (ref

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