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In conclusion, we found that ALC significantly reduced SREBP2 and HMGCR expression, leading to decreased de novo cholesterol synthesis, lower serum cholesterol levels in HCD-fed mice, and attenuated atherosclerotic progression

& Harries, M

Fetching molecular profile GlutathioneAlso known as: GSH, L--glutamyl-L-cysteinylglycine Mechanism of Action Glutathione acts as a central regulator of cellular redox balance by neutralizing reactive oxygen species (ROS) through its thiol group, participating in enzymatic detoxification reactions primarily via glutathione peroxidases and transferases, and maintaining mitochondrial stability

P.SagalovskiyI.GuoQ.NezosA.KapsogeorgouE

However, it should be noted that cells with high mitochondrial metabolism may be sensitive to the effects of elesclomol (132)