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Historically, the lack of standardized, skin-specific outcome measures has limited therapeutic progress in CLE and created uncertainty for regulatory approval

In other words, GABA-aberrant glutamate interactions induce loss of synapses, but glutamate metabolic changes can also injure neurons excitotoxically [15]

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Conclusion: If you or someone you know is experiencing symptoms like fatigue, nerve pain, or memory loss, dont ignore it

Others point to dehydration, since increased lipolysis generates metabolic water demands