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These include the complex equilibrium of various PTMs on histone lysine residues, the potential interplay between histone and nonhistone lactylation and their respective impacts on cellular function, and their distinct roles in the pathophysiology of IRI

Randomized Phase II study with cetuximab in combination with 5-fu and cisplatin or carboplatin vs

In chronic inflammatory diseases, such as MS, antioxidant defenses are overcome, which leads to oxidative stress [3]

This inflammatory state not only damages surrounding healthy cells but can also lead to excessive activation of the immune system, further exacerbating tissue damage (Byrns China et al., 2024