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Additionally, it participates in the regeneration of oxidized vitamin E, thereby enhancing the overall antioxidant defense system [45]

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After intraperitoneal administration of one single and three consecutive carbon tetrachloride doses of 2.0 ml/kg body weight (1:1 dilution in mineral oil) to Sprague-Dawley rats, the blood lactic acid levels were raised, whereas the administration of mineral oil did not increase them

These findings suggest that catalpol has significant beneficial effects on atherosclerosis and other vascular-related diseases

The crystal structures, along with the activity assays of UGT74F2 and UGT74F1 mutants, suggest that SA can bind in two different conformations, with each enzyme preferring a particular SA binding mode