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B12 is involved in approximately 100 functions including DNA, RNA, hormones, lipid and protein synthesis

Treatment with folic acid is ineffective and may instead result in worsening seizures (43

The importance of the adequate consumption of micronutrients is that they have a fundamental role in the immune system throughout life

Safety examinations are saved intensive and include serial hepatic, renal, cardiovascular function tests, haematology profiles and adverse event monitoring with special attention of combined administration of supplements with chemotherapeutics or endocrine agents rated to have organ-specific toxicity risk

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