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Why is sample handling so important when measuring intracellular glutathione levels

Zuzak E, Horecka A, Kieczykowska M, Dudek A, Musik I, Kurzepa J, Kurzepa J

Laurberg, P., Blow Pedersen, I., Knudsen, N., Ovesen, L

The study showed that rutin can target the Cys 151 of Keap1, and form an adduct with Keap1 which results in Nrf2 activation and upregulation of glutamate cysteine ligase, a glutathione biosynthesis rate-limiting enzyme which plays an important role in the endogenous antioxidant system (Sthijns et al., 2017)