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10.1016/j.jchromb.2018.11.001 267 ZhongK.ZhangH.-Q.FangY.-X.LanQ.-M.ZhouZ.-J.ZhaoY.-R.et al (2023)

Ying et al., 2024)

Varoglutamstat ( 17 , formerly PQ912), the first small molecule glutaminyl cyclase inhibitor to enter phase II clinical trials, targets an enzyme that catalyzes the conversion of glutamate to pyroglutamate at the N-terminus of A

Gold KA, Lee JJ, Ping Y, Behrens C, Liu D, Lee HY, Koo JS, Lotan R Solis L, Rinsurongkawong W, Stewart DJ, Hofstetter WL, Swisher SG , Lippman SM, Wistuba II, Hong WK, Kim ES