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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

albicans- induced ALI model, anesthetized mice were challenged with 1 10 6 or 3 10 6 (for survival monitoring) C

Although the final analysis and current expert consensus guidelines suggest that such patients may not require stem cell therapy, this conclusion remains open to challenge given the limited sample size