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The cages of these mice were covered with black paper except for the lid, and to minimize contact, the mice were only taken out of the cage once a week by one person to clean the cage 48,49

Statistical analysis The data in each table is shown as mean SE and calculated from three replicates

Foretz, M., Guigas, B., Bertrand, L., Pollak, M

The pckA gene, which encodes phosphoenolpyruvate carboxykinase (PEPCK), acts as a pathogenic factor for virulent bacteria (Liu et al., 2005)

In addition, since cysteine levels in the bone marrow where stress erythropoiesis occurs in SCD patients are unavailable, as a surrogate, we determined cystine levels in SCD mouse spleen, where stress erythropoiesis occurred