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Lysosomes, as well as late endosomes and autophagosomes, have a thin layer of lysosomal glycocalyx on their inner surfaces (77) that protects the membranes from being digested by the hydrolytic enzymes they contain (78)

Valori, C

10.1016/j.arr.2023.101858 64 RobbaC.BattagliniD.SamaryC

The GLP-1 pathway (semaglutides role): GLP-1 (glucagon-like peptide-1) is a hormone released in the gut after eating

This stability profile distinguishes it from many peptide-based research compounds and has contributed to interest in its biochemical persistence, signaling activity, and pathway-specific effects in mechanistic investigations