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What they found: 4,192 human genes change expression by 2 in response to GHK-Cu (31.2 % of the human genome) Of these 2,296 genes up-regulated , 1,896 down-regulated Pattern of changes: a rejuvenating signature, genes typically associated with ageing are down-regulated, regenerative genes up-regulated DNA repair , strong up-regulation of genes in BER, HR, NER pathways Mitochondrial biogenesis , increase in the number of mitochondria in cells Anti-apoptotic signal , protection against cell death Down-regulation of cancer signals , some oncogenes decreased Why it matters: This is the strongest evidence for the pleiotropic nature of GHK-Cu

Pellerin L, Magistretti PJ (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization

Dear valued customer, This is to let you know that there may be delay in the delivery of your order due to the Easter Holiday as full delivery operations will resume on Tuesday, 22nd April, 2025

I responded briefly to this question in one of my Dear Lyme WarriorHelp! columns

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