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Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

Xiong et al., 2016

The components of cell lysates and conditioned culture medium also impact SAM and SAH, albeit comparably less markedly than as seen for plasma (Figure 4)