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Independently of the type of diabetes involved, the available evidence suggests that the increase in serum oxidative stress is associated with the presence of microangiopathic, macroangiopathic and neuropathic complications of diabetes mellitus.12 Furthermore, the increased production of ROS in diabetic individuals worsens insulin action at the peripheral level and contributes to pancreatic beta cell dysfunction.15 Very few studies have investigated whether the antioxidant capacity in the saliva of diabetic patients differs from that of healthy subjects

The bodys antioxidant defense system includes antioxidant enzymes, such as superoxide dismutase and glutathione peroxidase

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The corresponding mean values for the Mae Sot group were 10.43 g/g creatinine, [37-39]

Some HBB alleles can cause genetic disorders