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Generally, NNMT overexpression decreases SAM and S-adenosyl-L-homocysteine (SAH) levels and alters SAM/SAH in vivo and in vitro in an obvious manner (96)

Diabetologia 58 (4), 799808

Increased fiber intake plays a significant role in improving blood glucose levels, lowering cholesterol, and promoting satiety

Monitoring: Regular colonoscopies, blood tests, and imaging are important for monitoring disease activity, medication safety, and cancer surveillance (long-standing Crohns colitis increases colorectal cancer risk)