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Other studies have demonstrated that MPTP activates the apoptotic cascade by inducing Bax and caspase-3, resulting in caspase-dependent programmed cell death [98, 99]

Among other considerations, quantitative aspects are important

It has to be kept in mind, however, that cystine can also be transported by EAATs (Hayes et al., 2005)

This may be due to the fact that the quercetin binds to either the COVID-19 spike protein at its host receptor region or the spike protein of the human angiotensin-converting enzyme 2 (ACE2) receptor interface, inhibiting the virus entry to cells and disrupting hostvirus interactions indicating its therapeutic potential (Smith and Smith 2020)

Curcumin acts synergistically with fluconazole to sensitize a clinical isolate of Candida albicans showing a MDR phenotype