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It also reduced pro-inflammatory cytokines (IL-6, TNF-, IFN-) and the expression of the p38 MAPK pathway

Surprisingly, both genes are down-regulated in response to chemicals, a condition where GSTs are usually over-expressed

To an extent, thats true

The inflammatory response is further exacerbated in lung injury, leading to diffuse damage to alveolar epithelial cells, decrease in lung surface-active substances, destruction of the alveolar walls, increased permeability of the basolateral membranes, accumulation of intra-alveolar fluid, accumulation of polymorphonuclear leukocytes, parenchymal cell damage, and interstitial edema (Meng et al., 2018)

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