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The cellular necrosis after an APAP overdose leads to release of cell contents, which includes molecules termed damage-associated molecular patterns (DAMPs) that can bind to pattern recognition receptors, e.g., toll like receptors, on macrophages and trigger formation of various cytokines and chemokines [8690]

For some people with severe allergies, exposure to an allergen can result in a life threatening reaction called anaphylaxis

The animals were housed on a 12-h light/dark cycle

Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression

HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING