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Furthermore, cellular activation promotes increased BIM expression in the absence of cell death induction, as for example observed in lipopolysaccharide (LPS)-activated neutrophilic granulocytes and lectin-activated T lymphocytes [55]

In optogenetic experiments, outliers and recordings that did not elicit at least a 70% of increment activity were removed from the analysis to minimize interference from non-orexinergic neurons

Increased production of tumor necrosis factor- by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells

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Treatment with marmelosin at both doses demonstrated a significant attenuation of these pathological changes, including reduced interstitial inflammation, ameliorated follicle cell injury, and improved islet architecture organization, corroborating previous findings