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Arjunolic acid and echitamine also showed moderate antiplasmodial activity, with IC 50 value of 22.5 and 16.3 g/ml, respectively [75]

Elevated oxidative stress tends to promote a pro-inflammatory M1 phenotype, while a more reduced environment facilitates M2 polarization, fostering tissue repair and immune regulation (62)

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Future research endeavours will likely focus on addressing these obstacles, particularly through the utilization of tissue-specific ligands that enhance stability and binding affinity to optimize targeting

Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention