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Among these, Farnesoid X Receptor (FXR) and Takeda G-protein Receptor 5 (TGR5) represent two critical BAs receptors (Wang et al., 2008)

A meta-analysis demonstrated that omega-3 fatty acid supplementation significantly reduces disease activity in adult SLE patients (with an average decrease of 0.9 points in SLEDAI scores) [100]

Gao Y, Kang K, Liu Y, Li N, Han Q, Liu H, Kong W, Zhang X, Huang R, Yang Z, Qi Z, Zheng J, Li M, Wang H, Li J, Liu R, Wang S, Zhang W, Zhao M, Yu K (2021) Mechanisms of renal-splenic axis involvement in acute kidney injury mediated by the 7nachr-nf-b signaling pathway

The research in the laboratory is also was also supported by grants from the NIGMS (P20GM139753 - Sub project 5203) to B.K.S, the National Heart, Lung, and Blood Institute (2T32HL115505-11) to A.G.S, and the Hawaii Community Foundations Ingeborg v.F