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Handog et al, in a single-arm study administered glutathione as lozenges for oral absorption in 30 women over an eight-week period and showed a significant reduction in melanin index

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A key future challenge, therefore, is to understand how the context dictated by cell type, metabolic state, and microenvironmental signals determines the functional outcome of lactylation, enabling the design of interventions that selectively target its pathogenic roles

Futur J Pharm Sci 9:113