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Due to the appearance of autoantibodies specific for various kinds of cytokines, such as autoantibodies against type I IFN, IFN, GM-CSF, IL-17A, IL-17F, IL-22, IL-23, and IL-6, patients are predisposed to various infectious diseases, as well as bacterial, fungal, or viral infections (124)

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Hence, the total nocturnal concentration of exogenous and endogenous melatonin (115.89 10 6 pg/ml + 50 pg/ml) compared to the total concentration of diurnal endogenous and exogenous melatonin (115.89 10 6 pg/ml + 20 pg/ml) would negligibly deviate by 2.58 10 5 %

To uncover associations with beta cell function, comparisons were made between these targeted proteomics measurements and changes in fasting C-peptide levels

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